preg — Neurospora crassa

Summary

NCU01738, symbol preg on chromosome 2 of Neurospora crassa, encodes a cyclin PHO80-like protein with cyclin-dependent protein serine/threonine kinase regulator activity and protein kinase binding. This gene is associated with the regulation of phosphate transport, phosphate metabolism, and phospholipid anabolism, as well as cell cycle control, downregulation of sister chromatid cohesion, and DNA-dependent transcription. The product localises to the CDK holoenzyme, mitotic spindle pole body, cell division site, cytosol, and nucleus. Studies of related genes in other species link the family to phosphate signalling and cell cycle regulation.