CYC1 — Magnaporthe oryzae 70-15

Summary

MoCYC1 (MGG_06685) on chromosome 1 of Magnaporthe oryzae 70-15 encodes a cytochrome c family protein with a Cyt_c-like domain, possessing electron transfer activity and heme binding. It is associated with mitochondrial electron transport chains, both from ubiquinol to cytochrome c and from cytochrome c to oxygen, and localises to the mitochondrial envelope lumen and cytoplasm. The gene is linked to appressorium formation, sporulation, filamentous growth, cell-cell adhesion, nucleosome assembly, nuclear export, and cell cycle control. Phenotypic associations include altered oxidative stress resistance, mitochondrial genome maintenance, respiratory metabolism, cell cycle progression, chromosome segregation, autophagy, vacuolar transport, and pseudohyphal growth. Studies of related genes in other species link the family to oxidative stress response.