HAT1 — Magnaporthe oryzae 70-15

Summary

MGG_06375 (MoHAT1) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a type B histone acetyltransferase catalytic subunit (EC 2.3.1.48) with H4 histone acetylase activity, histone binding, and chromatin binding. The gene is associated with appressorium formation, autophagy and its regulation, macroautophagy, double-strand break repair, DNA repair, telomeric silencing, translation, and cell growth. The product localises to the nucleus, cytoplasm, the pre-autophagosomal structure (PAS), the histone acetylase complex, and telomeric chromosome regions. MoHAT1 is linked to blast disease in rice (Oryza sativa). Related genes in other species connect it to histone acetylation and chromatin assembly.