DBP2 — Magnaporthe oryzae 70-15

Summary

MGG_06483 (DBP2/DBP8) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a DEAD-box RNA helicase with RNA helicase activity, RNA binding, and ATP hydrolase activity. The protein localises to the nucleolus, nucleus, and cytosol. It is associated with rRNA processing, sexual reproduction, mating, and digestion. Phenotypic associations link the gene to abnormal mitotic recombination, decreased mating-type switching, absent or abnormal sporulation efficiency, altered cell cycle progression (including increased S-phase rate, premature G1/S transition, delayed anaphase, and increased overall duration), delayed vegetative and exponential growth, increased thermotolerance and gamma ray resistance, altered chemical resistance, increased fermentative growth, increased carbon source utilisation, and increased protein/peptide modification rate. Related genes in other species are linked to oxidative stress response.

Annotations

Chromosome
4
Related genes
DBP2, NHP10, SRB2, RRM3, RAD57, MCD1, DPB11, UBC13
GO terms
Sexual Reproduction, Digestion, RNA Binding, ATP Binding, Nucleus, Cytosol, RNA Helicase Activity, Mating
Publications
28357333, 28336179, 27840029, 11779796, 28383696, 19189942, 19282251, 19233144
Traits
RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, UTILIZATION OF CARBON SOURCE: INCREASED RATE, NUCLEAR POSITION: ABNORMAL