YAK1 — Magnaporthe oryzae 70-15

Summary

MoYAK1 (MGG_06399) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a CMGC/DYRK/YAK protein kinase. It is associated with cyclin-dependent protein kinase activity, phosphatidylinositol phosphate binding, dual-specificity protein kinase activity, protein tyrosine kinase activity, protein kinase activity, protein serine kinase activity, protein serine/threonine kinase activity, and ATP binding. The gene is associated with positive regulation of mRNA cis splicing via spliceosome, response to mitotic DNA integrity checkpoint signaling, downregulation of attachment of spindle microtubules to mitotic chromosome, downregulation of mitotic spindle elongation, regulation of linear element maturation, meiotic DNA replication checkpoint effector process, negative regulation of primary cell septum biogenesis, upregulation of mitotic cell cycle DNA replication, downregulation of mitotic telomere tethering at nuclear periphery, negative regulation of anaphase-promoting complex-dependent catabolic process, regulation of cellular response to glucose starvation, upregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination, downregulation of protein localisation in plasma membrane, response to mitotic G2 DNA damage checkpoint signaling, positive regulation of protein breakdown, regulation of establishment or maintenance of bipolar cell polarity, negative regulation of mitotic DNA replication initiation, and downregulation of protein localisation to cell tip. MoYAK1 is linked to increased duration of M phase, delayed telophase, premature meiosis