ACB1 — Magnaporthe oryzae 70-15

Summary

MoACB1 (MGG_06177) on chromosome 3 of Magnaporthe oryzae 70-15 encodes an acyl-CoA-binding domain-containing protein, a member of the acyl-CoA-binding protein superfamily. The product is annotated with long-chain fatty acyl-CoA and fatty-acyl-CoA binding activities and is associated with very-long-chain fatty acid anabolism, fatty acid metabolism, ER-phagy, autophagy, and hyphal growth. It localises to the cytosol and nucleus. The gene is linked to numerous phenotypes including altered respiratory metabolism, mitochondrial genome maintenance and distribution, cell cycle progression, biofilm formation, vegetative and invasive growth, stress resistance, and carbon source utilisation. Studies of related genes in other species connect the family to autophagy, filamentous growth, sporulation, and thermotolerance.