BD — Magnaporthe oryzae 70-15

Summary

MoBD (MGG_06154) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a small GTPase of the Ras-type family, possessing GTPase activity, GTP binding, and G protein activity. The gene is associated with Ras protein signal transduction, the MAPK cascade, protein farnesylation, and the establishment or maintenance of cell polarity. It is linked to appressorium formation, invasive growth, conidium formation, spore germination, hyphal growth, sporulation, melanin anabolism, and programmed cell death. Associations also include vacuolar transport, secretion, morphogenesis, and deubiquitination. The product localizes to the plasma membrane. Phenotypic associations include decreased vacuolar transport rate, absent bipolar budding, decreased redox state, increased mating-type switching, decreased entry into G0, absent osmotic and oxidative stress resistance, and decreased budding rate. Related genes in other species are linked to reduced virulence and the oxidative stress response.