nit1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_07386 (symbol nit1) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a nitrilase family protein, containing nitrilase/cyanide hydratase and C-N hydrolase domains. The gene product exhibits multiple enzyme activities annotated on this gene, including nitrilase, cyanide hydratase, arylacetonitrilase, hydro-lyase, and aminoacyl-tRNA ligase activities. It is associated with nitrate metabolism and nitrate assimilation. Studies of related genes in other species link the nitrilase family to cyanide hydratase activity (EC 4.2.1.66) and nitrilase activity (EC 3.5.5.1 and 3.5.5.5), as well as to traits such as nitrate transport, nitrogen content, and molybdenum content. Phenotypic associations from related species connect the family to altered autophagy, mitophagy, heat sensitivity, chronological lifespan, hyperosmotic stress resistance, vegetative growth rate, and competitive fitness.