LIP5 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_07635 (LIP5) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a carboxylesterase belonging to the carboxylesterase B and AB hydrolase families, with chlorogenate hydrolase, carboxylesterase, and triacylglycerol lipase activities. The gene is associated with lipolysis, lipid metabolism, cholesterol metabolism, and secretion, and its product is localised extracellularly. Studies of related genes in other species link the family to carboxylesterase and cholinesterase activities, as well as to triacylglycerol lipase (EC 3.1.1.3) and carboxylesterase (EC 3.1.1.1) functions, and to an association with unaffected pathogenicity. The family has also been connected to plant hosts and to the pathogen grey mold.