TRI1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoTRI1 (FOXG_08848) on chromosome 2 of Fusarium oxysporum f. sp. lycopersici encodes a protein containing SWIB and DEK_C domains, with RNA polymerase I cis-regulatory region sequence-specific DNA binding and general RNA polymerase I transcription factor activity. It is associated with transcription initiation from the Pol I promoter and transcription of nuclear rRNA large Pol I transcript, and localises to the UAF complex, nucleus and cytosol. The gene is linked to numerous phenotypes including increased gamma ray and UV resistance, decreased X-ray and ionizing radiation resistance, delayed vegetative growth, absent spore germination, abnormal spore wall formation, decreased colony size, increased osmotic stress resistance, decreased apoptosis, and altered cell cycle progression, meiotic recombination, endocytosis, mitophagy, nutrient uptake, vacuolar transport, mitochondrial genome maintenance, and mutation frequency. Related genes in other species are linked to increased nucleolar size and stress resistance.