MT1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoMT1 (MT1) of Fusarium oxysporum f. sp. lycopersici 4287, located on chromosome 9, encodes a methyltransferase belonging to the CMAS domain and SAM-dependent methyltransferase superfamily. The gene is associated with methyltransferase activity and is linked to glucosylceramide anabolism, sphingolipid metabolism, methylation, and filamentous growth. Its product localises to the plasma membrane, membrane, and extracellular vesicles. Studies of related genes in other species connect the family to C-9 methyltransferase activity (EC 2.1.1.317) and to both reduced virulence and unaffected pathogenicity in different contexts, as well as to fusarium head blight. The gene has also been linked to expression changes during tomato infection (Fol:DEG_4DPI_vs_In_vitro).