GAS1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_10173 (GAS1) on chromosome 11 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein of the Egh16-like family with monooxygenase activity and metal binding capability. The product is an apoplastic effector localized to both the cytoplasm and extracellular. This gene is associated with expression during tomato infection at 2, 4, and 6 days post-inoculation, as well as under in vitro conditions. Related genes in other species link the family to reduced virulence and to the enzyme classification 1.14.99.56. The GAS1 family has been associated with blast disease in rice and with pathogens including Verticillium dahliae and other Fusarium oxysporum strains, with differential expression patterns observed in tomato infections.