CHS7 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoCHS7 (FOXG_10314) on chromosome 7 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with unfolded protein binding activity (GO:0051082). The gene is associated with cell wall biogenesis and organization, chitin anabolism, homologous recombination, protein folding, protein transport, and ER membrane localization. Phenotypic associations include altered chitin deposition, abnormal spore wall formation and cell wall morphology, absent filamentous and pseudohyphal growth, increased biofilm formation and sporulation efficiency, altered mating response and mating efficiency, increased viability and vegetative growth, altered mitotic recombination rates, increased resistance to alkaline pH, acid pH, hyperosmotic stress, and hydrostatic pressure, decreased cold sensitivity, decreased apoptosis, decreased exponential-phase growth, and altered protein transport and silencing. Related genes in other species link the family to reduced virulence and decreased desiccation resistance.