lip1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_11103 (lip1) on chromosome 1 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a carboxylesterase with an AB hydrolase domain and carboxylesterase B family signature, annotated for carboxylesterase and triacylglycerol lipase activity. The gene is associated with lipolysis, lipid metabolism, cholesterol metabolism, and secretion, and its product is localized extracellularly. Expression of lip1 has been connected to the fungus during in vitro growth and at 2, 4, and 6 days post inoculation of tomato. Studies of related carboxylesterase/lipase family members in other species link the family to EC 3.1.1.1 and 3.1.1.3 activities and to unaffected pathogenicity, though this has not been established for lip1 itself.