MT1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoMT1 (MT1) of Fusarium oxysporum f. sp. lycopersici 4287 on chromosome 10 encodes a methyltransferase belonging to the SAM-dependent methyltransferase superfamily, with methyltransferase activity. The gene is associated with glucosylceramide anabolism, sphingolipid metabolism, methylation, and filamentous growth. Its product localises to the plasma membrane, membrane, and extracellular vesicles. FoMT1 is linked to expression changes during tomato infection at 2, 4, and 6 days post-inoculation, as well as in vitro. Studies of related genes in other species connect the family to reduced virulence, though also to unaffected pathogenicity, and to fusarium head blight in wheat. The gene is also linked to Verticillium species and to plants including tomato, maize, and Arabidopsis thaliana through sequence similarity.