ADH1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoADH1 (FOXG_12790) on chromosome 9 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with aldo-keto reductase (NAD) activity and zinc binding, containing ADH-like and PKS_ER domains. The gene is associated with acetaldehyde breakdown, ethanol breakdown, threonine breakdown, and cellular response to farnesol. Its product localises to the cytoplasm, mitochondrial lumen, extracellular space, and fungal biofilm matrix. FoADH1 is linked to the related genes patD and alcC. Studies of related genes in other species, based on sequence similarity, connect it to alcohol dehydrogenase (EC 1.1.1.1) activity and CAD-like domains.