nit1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_13434 (symbol nit1) on chromosome 12 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a nitrilase family protein containing a nitrilase/cyanide hydratase active-site signature and a C-N hydrolase domain. The enzyme exhibits cyanide hydratase, arylacetonitrilase, nitrilase and hydro-lyase activities, and is associated with nitrate metabolism and nitrate assimilation. Sequence similarity connections to related genes in other species associate the family with nitrate transport, nitrogen content, molybdenum content, and nitrate uptake, as well as with altered autophagy, mitophagy, heat sensitivity, hyperosmotic stress resistance, vegetative growth rate, competitive fitness, and chemical resistance.