LIP1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_14401 (LIP1) on chromosome 15 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a carboxylesterase belonging to the alpha/beta hydrolase family, with annotated chlorogenate hydrolase, carboxylesterase, and triacylglycerol lipase activities. The gene is associated with lipolysis, lipid metabolism, and secretion, and its product is localized to the extracellular space. LIP1 is linked to the related gene LIP3. Studies of related genes in other species, based on sequence similarity, connect the family to chlorogenate hydrolase (EC 3.1.1.42), carboxylesterase (EC 3.1.1.1), and triacylglycerol lipase (EC 3.1.1.3) activities, and to an unaffected pathogenicity phenotype. The family has also been identified in plant-pathogenic contexts including Fusarium avenaceum, grey mold, and hosts such as tomato and carnation.