NIT1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoNIT1 (FOXG_11025) on chromosome 1 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with C-N hydrolase domains. The gene is associated with cyanide hydratase, arylacetonitrilase, nitrilase, and hydro-lyase activities, and with cyanide breakdown, nitrate metabolism, and nitrate assimilation. Expression of FoNIT1 has been detected during in vitro growth and at 2, 4, and 6 days post-inoculation in tomato. Studies of related genes in other species link the family to cyanide detoxification and nitrogen recycling, though pathogenicity was unaffected in those relatives.