lip1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_09912, designated lip1, is located on chromosome 11 of Fusarium oxysporum f. sp. lycopersici 4287. It encodes a carboxylesterase belonging to the alpha/beta hydrolase family, with annotated chlorogenate hydrolase, carboxylesterase, and triacylglycerol lipase activities. The gene is associated with lipolysis, cholesterol metabolism, and secretion, and its product is linked to extracellular, cytosolic, and nuclear localisation. Related genes include LIP3 and LIP4. Studies of related genes in other species connect them to carboxylesterase and lipase activities (EC 3.1.1.1, 3.1.1.3, 3.1.1.42) and to a lack of effect on pathogenicity in some contexts.