LIP1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_09686, symbol LIP1, on chromosome 11 of Fusarium oxysporum f. sp. lycopersici 4287, encodes a carboxylesterase belonging to the alpha/beta hydrolase family, with annotated chlorogenate hydrolase, carboxylesterase, and triacylglycerol lipase activities. The gene is associated with lipolysis, lipid metabolism, cholesterol metabolism, and secretion, and its product is localised extracellularly. LIP1 is linked to the related genes LIP3, ANIA_07947, and chlE. Studies of related genes in other species connect it to the lipase GDXG active site and type-B carboxylesterase/lipase domains, as well as to EC numbers 3.1.1.42, 3.1.1.1, and 3.1.1.3. Family-level evidence also associates LIP1 with unaffected pathogenicity in some contexts and with host plants such as tomato.