ESF1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoESF1 (FOXG_09191) on chromosome 9 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a nucleolar RNA-binding protein belonging to the NUC153 domain family. The gene is associated with rRNA processing and localises to both the nucleolus and nucleus. FoESF1 is linked to a wide range of cellular and developmental phenotypes, including abnormal cell cycle progression, particularly in G1 phase, altered cell size and shape, and changes in filamentous, invasive and vegetative growth. It is also associated with increased mating response, decreased cold sensitivity, increased desiccation resistance, altered telomere length, and decreased killer toxin resistance. Related genes in other species link the family to pre-rRNA processing and ribosome biogenesis, while sequence similarity connects FoESF1 to the RPA34 subunit of RNA polymerase I and the RRM_ESF1 domain.