ADH1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoADH1 (FOXG_07414) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a zinc-binding protein with aldo-keto reductase (NAD) activity, containing ADH_Zn_CS, ADH-like, and PKS_ER domains. The gene is associated with alcohol metabolism, acetaldehyde breakdown, ethanol breakdown, threonine breakdown, and cellular response to farnesol. Its product localises to the cytoplasm, mitochondrial lumen, extracellular space, and fungal biofilm matrix. FoADH1 is linked to the related genes patD and alcC. Studies of related genes in other species, including Fusarium and Verticillium species, connect the family to the EC 1.1.1.1 enzyme class.