LIP1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_07008 (LIP1) on chromosome 6 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a carboxylesterase with chlorogenate hydrolase, carboxylesterase, and TAG activity, belonging to the carboxylesterase B and alpha/beta hydrolase families. The gene is associated with lipolysis, lipid metabolism, cholesterol metabolism, and secretion, and its product is localised to the extracellular space. LIP1 has been linked to the related genes LIP3, ANIA_07947, and chlE. Related genes in other species connect the family to lipase GDXG and acetylcholinesterase-related enzymes, as well as EC 3.1.1.42, 3.1.1.1, and 3.1.1.3, and to an effector function. Phenotype evidence from related genes indicates the family is associated with unaffected pathogenicity, and the family has been linked to hosts such as tomato, carnation, gerbera, and lima bean, as well as to grey mold and Verticillium species.