SIB1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoSIB1 (FOXG_06448) on chromosome 2 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with peptide synthase and ligase activity that binds phosphopantetheine. The gene is associated with ferrichrome anabolism, amino acid activation for nonribosomal peptide biosynthesis, secondary metabolite biosynthesis, defense response, and cellular response to iron ion starvation. Its product localizes to the cytoplasm and cytosol. Studies of related genes in other species link the family to reduced virulence and unaffected pathogenicity, as well as associations with vascular wilt, fusarium head blight, and diseases of maize and cotton, though these connections are not established for FoSIB1 itself.