pda1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_06001 (symbol pda1) on chromosome 2 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a thiamine diphosphate-binding dehydrogenase with pyruvate dehydrogenase (lipoamide) activity and metal-binding capacity. The gene product localises to the mitochondrial lumen and the pyruvate dehydrogenase complex. It is associated with the pyruvate dehydrogenase pathway, translation elongation, and mating. Studies of related genes in other species link the family to the same enzyme class (EC 1.2.4.1) and the alpha-ketoacid dehydrogenase E1 component domain.