FBP1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_05961 (FBP1, FoFBP1) in Fusarium oxysporum f. sp. lycopersici 4287 on chromosome 2 encodes a class-1 fructose-bisphosphatase with FBPtase, fructose_bisphosphatase_AS, FBPase_N, and FBPase_C_dom domains, and carries fructose 1,6-bisphosphate 1-phosphatase activity and metal binding. The gene is associated with gluconeogenesis, fructose metabolism, cellular response to glucose starvation, sucrose anabolism, proteolysis, proteasome degradation, and invasive growth, and localises to the cytoplasm, cytosol, and nucleus. Phenotypic associations include abnormal pseudohyphal growth, increased entry into G0 stationary phase, increased respiratory metabolism, increased hydrostatic pressure resistance, decreased mitochondrial transport, and abnormal colony shape. Related genes in other species link the family to oxidative stress response.