SNF1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_01209 (SNF1) on chromosome 1 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein serine/threonine kinase with protein kinase A activity, ATP binding, and identical protein binding. It is associated with the CAMKK-AMPK signaling cascade, cellular response to glucose starvation, regulation of invasive growth in response to glucose limitation, upregulation of gluconeogenesis and macroautophagy, downregulation of TORC1 signaling, positive regulation of pseudohyphal growth, single-species surface biofilm formation, fungal-type cell wall assembly, mitotic spindle orientation, negative regulation of translation and inositol phosphate biosynthesis, and mycose catabolism. The product localizes to the nucleus, cytoplasm, cytosol, vacuolar membrane, nuclear membrane, perinuclear space, mitotic spindle pole body, cellular bud neck septin ring, and the nucleotide-activated protein kinase complex. Studies of related genes in other species link the family to virulence, pathogenicity, and disease phenotypes including stem canker, leaf spot, and white mold.