BRLA — Fusarium oxysporum f. sp. lycopersici 4287
Summary
FoBRLA (FOXG_02103) on chromosome 5 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a transcription factor with sequence-specific DNA-binding activity. This gene is associated with mating behavior, parasexual conjugation, pseudohyphal growth regulation, sporocarp development, biofilm formation, phenotypic switching, immune evasion, and development of the symbiont in the host. It is linked to the regulation of secondary metabolite biosynthesis, cellular response to nutrient levels, and galactose metabolism. The encoded protein localizes to the nucleus, cytoplasm, membrane, chromatin, and the Tec1p-Ste12p-Dig1p and Ste12p-Dig1p-Dig2p complexes. Studies of related genes in other species link the family to sporogenesis, germination rate, oxidative stress response, and loss of pathogenicity.
Annotations
- Chromosome
- 5
- Related genes
- YER109C, BRLA, BrlA, PBS2, SLT2, MCM1, UPC2, IRE1
- GO terms
- Sequence-specific DNA Binding, DNA-binding Transcription Factor Activity, RNA Polymerase II-specific, Regulation Of DNA-templated Transcription, Zn binding, Nucleus, Fungal-type Cell Wall Organization, Cytoplasm, DNA Binding
- Publications
- 8196622, 34849884, 27358400, 19233144, 32737079, 27458021, 22496730, 19297522
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, NUCLEAR POSITION: ABNORMAL, RESISTANCE TO CHEMICALS: NORMAL