FGR3 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_02573 (FGR3) on chromosome 5 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with a CAT-like domain superfamily and multiple annotated enzymatic activities, including acyltransferase, lyase, transferase, and isomerase activities, as well as pigment binding and metal binding. The gene is associated with the biosynthesis of emericellamide A, ergot alkaloids, and fumigaclavine C, and is linked to fatty acid beta-oxidation, immune response, and virus-induced post-transcriptional gene silencing. Its product localises to mitochondria. The gene is also associated with the TRI101 protein, which centres on T-2 toxin modification, and shows expression changes during tomato infection at 2, 4, and 6 days post-inoculation compared to in vitro conditions. Related genes in other species link the gene family to similar secondary metabolism and pathogenicity processes.