DBF2 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoDBF2 (DBF2) on chromosome 8 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein serine/threonine kinase with AGC-kinase and Pkinase_C domains. The gene is associated with regulation of FSM assembly, negative regulation of protein localization to medial cortex, upregulation of nuclear migration during mitotic telophase, upregulation of mitotic spindle elongation, adiposome localization to FSM membrane leading edge, upregulation of mitotic actomyosin contractile ring contraction, regulation of protein secretion, actomyosin organization, lipid raft organization, upregulation of filamentous growth of a population of unicellular organisms in response to heat, mitotic cytokinesis checkpoint, maintenance of protein location in cell cortex of cell tip, cellular salinity response, positive regulation of primary cell septum biogenesis, positive regulation of filamentous growth, upregulation of single-species biofilm formation on inanimate substrate, upregulation of exocytosis, and positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape. It is linked to the spindle, actomyosin contractile ring intermediate layer, growing cell tip, hyphal tip, cytoskeleton, cellular bud tip, meiotic spindle pole body, SPB, mitotic actomyosin contractile ring, and cross wall. Phenotypic associations include absent septum formation, delayed chromosome segregation, abnormal cell cycle progression, decreased lifespan, and altered redox state. Studies of related genes