NIA — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_03770 (symbol NIA, also known as niaD) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with nitrate reductase (NADPH) activity, sulfite oxidase activity, cytochrome-b5 reductase activity acting on NADH and on NAD(P)H, NADH dehydrogenase activity, transferase activity, FAD binding, heme binding, moco binding, molybdenum ion binding, and redox activity. The gene is associated with nitrate assimilation, anaerobic respiration, nitric oxide anabolism, sulfur metabolism, protein histidyl modification to diphthamide, mcm5 modification, and invasive growth. Its product localizes to the mitochondrial outer membrane. Studies of related genes in other species link the family to nitrate uptake, molybdenum content, and unaffected pathogenicity, with connections to fusarium wilt in tomato.