CPR — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_04266 (CPR) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with CysJ-like_FAD-binding, NADPH_Cyt_P450_Rdtase_alpha, Flavoprot_Pyr_Nucl_cyt_Rdtase, OxRdtase_FAD/NAD-bd, Riboflavin_synthase-like_b-brl, FAD-bd_FR_type, and FNR_nucleotide-bd domains. It exhibits NADPH-hemoprotein reductase, electron transfer, and oxidoreductase activities, among others. The gene is associated with homocysteine metabolism, benzoate breakdown, nitric oxide anabolism, fumonisin anabolism, ergosterol anabolism, demethylation, iron-sulfur cluster assembly, and the cellular response to oxidative stress. Its product is linked to localisation at the mitochondrial outer membrane, ER membrane, mitochondria, plasmalemma, cytosol, and nucleus. Related genes in other species connect the CPR family to EC 1.6.2.4 activity, and expression data from tomato infections suggest the gene is differentially regulated during early (2–6 days post-inoculation) stages of pathogenesis.