AMT1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoAMT1 (FOXG_04437) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes an ammonium transporter family protein containing an AmtB-like domain and ammonium transport signature. The gene product exhibits methylammonium transmembrane transporter and ammonium channel activities, and is associated with ammonium import across the plasma membrane, as well as ammonium and methylammonium membrane transport. It localises to the plasma membrane, fungal-type vacuole and Golgi complex. FoAMT1 is linked to numerous phenotypes including abnormal biofilm formation, increased virulence, increased sporulation, altered cell cycle progression, abnormal autophagy and pexophagy, decreased nitrogen source utilisation, and abnormal respiratory metabolism. The gene is also associated with altered chemical compound accumulation, small molecule transport, filamentous growth, flocculation, and plasma membrane morphology.