ctf1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_04578 (symbol ctf1) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a Zn2Cys6 DNA-binding transcription factor, a member of the Zn2-C6 fungal-type DNA-binding superfamily. The encoded product possesses DNA-binding transcription factor activity specific to RNA polymerase II, binds zinc, and localises to the nucleus. It is associated with positive regulation of metabolism, secretion, and DNA-dependent transcription. The gene is linked to the related genes ctf1, ZC253, ADA-3, and the proteins ads-1 and TRF1. Sequence-similarity evidence from related genes in other species connects the family to secondary metabolite regulation and to the phenotype unaffected pathogenicity, as well as to associations with hosts such as barley, rice, and wheat, and diseases including blast and fusarium ear blight.