CHS1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoCHS1 (CHS1) on chromosome 7 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a chitin synthase, an enzyme with chitin synthase activity that contains chitin synthase functional and N-terminal domains. The gene is associated with cell wall biogenesis and organization, hyphal growth, conidia formation, ascospore wall assembly, cell septum assembly and positioning, septum digestion after cytokinesis, and chitin anabolism. The encoded protein localizes to the chitosome, hyphal tip, cross wall, cell periphery, and plasma membrane. FoCHS1 is linked to abnormal chitin deposition, septum formation, spore wall formation, budding, cell fusion, cell cycle progression, and decreased flocculation and adhesion, as well as increased respiratory and fermentative metabolism. Studies of related genes in other species connect the chitin synthase family to polysaccharide content and vegetative growth.