NIT3 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoNIT3 (FOXG_05167) on chromosome 7 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a C-N hydrolase family protein with bis(5'-adenosyl)-triphosphatase and ω-amidase activities. The gene is associated with nitrate assimilation, diadenosine triphosphate breakdown, glutamine and oxaloacetate metabolism, and cellular detoxification. Its product has been linked to mitochondrial, cytosolic and nuclear localisation. Expression of FoNIT3 has been detected during tomato infection at 2, 4 and 6 days post-inoculation, as well as under in vitro conditions. Studies of related genes in other species connect the family to altered phosphate content, oxidative stress response, increased biofilm formation, increased competitive fitness, and altered chemical resistance.