SOR1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoSOR1 (FOXG_05699) on chromosome 2 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with L-iditol 2-dehydrogenase (NAD+) and D-xylulose reductase activities, containing SDH-like and ADH-like domains. The gene is associated with xylitol breakdown to xylulose 5-phosphate, D-xylose metabolism and breakdown, sorbitol breakdown, and fructose anabolism, and the product localises to the cytosol. Phenotypic associations include increased fermentative growth, decreased anaerobic growth rate, decreased hyperosmotic and oxidative stress resistance, altered chemical compound accumulation, decreased vegetative growth, and increased chronological lifespan. The gene is also linked to altered competitive fitness, abnormal protein/peptide distribution, auxotrophy, and increased resistance to some chemicals. Studies of related genes in other species connect the family to D-xylulose reductase activity.