NIAD — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoNIAD (FOXG_04181) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a nitrate reductase with sulfite oxidase, cytochrome-b5 reductase, and NADH dehydrogenase activities, binding molybdenum, FAD, and heme. The gene is associated with nitrate assimilation, anaerobic respiration, nitric oxide anabolism, sulfur metabolism, invasive growth, and protein histidyl modification to diphthamide. Its product localises to the mitochondrial outer membrane, endoplasmic reticulum, and plasmalemma. Expression has been detected at 2, 4, and 6 days post inoculation in tomato. Studies of related genes in other species link the family to nitrate transport and uptake, molybdenum content, and fusarium wilt, though pathogenicity is unaffected in some relatives.