ADH1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoADH1 (FOXG_03863) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici encodes a protein with aldo-keto reductase (NAD) activity and zinc binding, containing ADH-like, PKS_ER, and NAD(P)-binding domains. The gene is associated with the breakdown of acetaldehyde, ethanol, and threonine, as well as the cellular response to farnesol. Its product localises to the cytoplasm and extracellular space. FoADH1 is linked to the related genes patD, alcC, and multiple alcohol dehydrogenase genes. Expression of FoADH1 has been detected during in vitro growth and at 2, 4, and 6 days post inoculation in tomato, connecting the gene to the fungal infection process. Related genes in other species assign the family to EC 1.1.1.1.