NRP1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoNRP1 (FOXG_02027) on chromosome 5 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein with 3'-5' exoribonuclease activity and mRNA binding, containing Nrp1_RRM, RNaseH-like, and zinc finger RanBP2 domains. The gene is associated with regulation of heterochromatin assembly, RNA-dependent gene silencing, chromatin organization, and cellular response to thermal stimulus. Its product localizes to the nucleus, cytoplasm, stress granules, and protein aggregate centers. FoNRP1 is linked to numerous phenotypes including increased apoptosis, decreased filamentous and invasive growth, altered prion inheritance, increased telomere length, and increased transposable element transposition. Associations with root dry weight and necrotic cell death have also been recorded. Related genes in other species connect the family to oxidative stress response.