PAB1 — Fusarium oxysporum Fo47

Summary

FOZG_10022 (PAB1) in Fusarium oxysporum Fo47 encodes a protein containing Nop4p_RRM3, RRM_dom, Nucleotide-bd_a/b_plait_sf, and RBD_domain_sf domains. The product exhibits poly(A) binding, poly(U) binding, mRNA 3′-UTR binding, U1 snRNP binding, RNA nuclease inhibitor activity, phase separation nucleator activity, promoter-specific chromatin binding, and mRNA binding. It is associated with regulation of translational initiation, regulation of nuclear-transcribed mRNA poly(A) tail shortening, nuclear-transcribed mRNA poly(A) tail shortening, mRNA 3′-end processing, regulation of translation, mRNA transport, mRNA cis splicing via spliceosome, mRNA processing, and rRNA processing. The protein localises to the nucleus, nucleolus, cytoplasm, cytosol, ribosome, post-mRNA release spliceosomal complex, stress granule, RNP, and spliceosome complex. PAB1 is linked to numerous spliceosome-related genes such as SYF2, prp19, and cwc15. Related genes in other species link the family to apoplastic and cytoplasmic effector functions. The gene shows differential expression during host infection, being associated with Fo47 at 24 and 96 hours post-inoculation compared to in vitro conditions.