CP1 — Fusarium oxysporum Fo47

Summary

FoCP1 (FOZG_11630) from Fusarium oxysporum Fo47 encodes a serine carboxypeptidase belonging to the peptidase S10 and alpha/beta hydrolase families. The gene is associated with proteolysis, zymogen activation, and protein catabolic processes in the vacuole, as well as monocarboxylic acid and antibiotic anabolism. It localises to the fungal-type vacuole, plasma membrane, and side of membrane. Phenotypic associations link FoCP1 to altered cell death, autophagy, endocytosis, cytokinesis, nuclear fusion during mating, prion inheritance, thermotolerance, lifespan, and chemical compound accumulation. The gene is also connected to abnormal Golgi morphology, decreased ribophagy and mitophagy, and increased aneuploidy. Related genes in other species are linked to apoplastic effector function and floral organ identity traits.