csx1 — Fusarium oxysporum Fo47

Summary

FOZG_12790 (csx1, also known as pab1) in Fusarium oxysporum Fo47 on chromosome JH717904 encodes a protein with RNA-recognition motif (RRM) domains. The gene product binds poly(A) and poly(U) RNA, localizes to the nucleus, cytoplasm, stress granules, and the U1 snRNP, and is associated with mRNA processing, splice site recognition, 3'-UTR-mediated mRNA stabilization, regulation of translation, mRNA transport, and positive regulation of gene expression. It is linked to cellular response to oxidative stress and regulation of mRNA stability during oxidative stress. The gene is connected to numerous related genes including SYF2, prp19, and pkc1. Studies of related genes in other species link the family to lethal phenotypes and invasive pulmonary aspergillosis, though these associations are not established for this specific gene.