CP1 — Fusarium oxysporum Fo47

Summary

FoCP1 (FOZG_14575) in Fusarium oxysporum Fo47 encodes a serine carboxypeptidase, belonging to the peptidase S10 family with an AB hydrolase domain. The gene is associated with proteolysis, zymogen activation, phytochelatin anabolism, and protein catabolism in the vacuole. It is linked to the fungal-type vacuole lumen and extracellular localisation, as well as cellular response to nitrogen starvation. Phenotypic associations include increased acquired thermotolerance, altered cell death, abnormal autophagy, decreased ribophagy, and effects on prion inheritance, lifespan, cytokinesis, and nuclear fusion during mating. Studies of related genes in other species link the family to apoplastic effector function and EC 3.4.16.5 activity, though these are not established for FoCP1 itself.