CP1 — Fusarium oxysporum Fo47

Summary

FoCP1 (FOZG_02414) on chromosome JH717897 of Fusarium oxysporum Fo47 encodes a serine carboxypeptidase belonging to the peptidase S10 family, with serine carboxypeptidase activity. The gene is associated with proteolysis, zymogen activation, and protein catabolic processes in the vacuole, and localises to the fungal-type vacuole lumen and plasma membrane. It is linked to antibiotic and monocarboxylic acid anabolism. Phenotypic associations include altered cell death, autophagy, endocytosis, cytokinesis, prion inheritance, nuclear fusion during mating, and increased lifespan. The gene is also connected to entry into G0 phase, acquired thermotolerance, and abnormal Golgi morphology. Studies of related genes in other species link the family to apoplastic effector functions and carboxypeptidase activity (EC 3.4.16.5/6).