CP1 — Fusarium oxysporum Fo47

Summary

FoCP1 (FOZG_04710) in Fusarium oxysporum Fo47 encodes a serine carboxypeptidase belonging to the peptidase S10 and alpha/beta hydrolase families, with annotated serine carboxypeptidase activity and involvement in proteolysis. The protein is associated with the fungal vacuole, plasma membrane, and extracellular side of the membrane. This gene is linked to numerous phenotypes including altered cell death, autophagy, endocytosis, protein secretion, nuclear fusion during mating, prion inheritance, and lifespan, as well as abnormal Golgi morphology and cytokinesis. It is also associated with chemical compound accumulation and ribophagy. Studies of related genes in other species link the family to carboxypeptidase Y activity (EC 3.4.16.5/6) and apoplastic effector function, though these associations are not established for FoCP1 itself.