SC — Fusarium oxysporum Fo47

Summary

FoSC (FOZG_08406) in Fusarium oxysporum Fo47 encodes a bifunctional enzyme with ATP:sulfate adenylyltransferase and adenylylsulfate kinase activities, placing it in the sulfate assimilation pathway for cysteine and hydrogen sulfide biosynthesis. The gene is associated with numerous cellular processes and traits, including increased vegetative growth, exponential growth rate, and pseudohyphal growth, as well as altered autophagy, pexophagy, and prion inheritance. It is linked to increased hyperosmotic stress resistance, decreased cold sensitivity, increased survival in stationary phase, and increased telomere length. Associations also include abnormal endomembrane system morphology, altered cell cycle progression in G1 phase, and changes in respiratory and fermentative metabolism. Studies of related genes in other species connect the family to sulfate adenylyltransferase function.