PAB1 — Fusarium oxysporum Fo47

Summary

FOZG_08852 (PAB1) in Fusarium oxysporum Fo47 on chromosome JH717900 encodes a protein with RRM and PABP domains, and is annotated with poly(A) binding, poly(U) binding, mRNA 3′-UTR binding, and RNA binding molecular functions. The gene is associated with regulation of translation, mRNA transport, and mRNA processing, and its product localizes to stress granules, ribonucleoprotein complexes, the cytosol, and the nucleus. PAB1 is linked to numerous related genes including SYF2, prp19, and pkc1, and has been connected to expression changes during host infection (Fo47:24HPI and Fo47:96HPI). Studies of related genes in other species associate PAB1-related sequences with lethal pathogen phenotypes and invasive pulmonary aspergillosis, though these findings are not established for this specific gene.