CP1 — Fusarium oxysporum Fo47

Summary

FoCP1 (FOZG_11037) on chromosome JH717902 of Fusarium oxysporum Fo47 encodes a serine carboxypeptidase belonging to the peptidase S10 and alpha/beta hydrolase families, with serine carboxypeptidase activity. The gene is associated with proteolysis and apoptotic processes, and its product localises to the trans-Golgi network. FoCP1 has been linked to numerous phenotypes including abnormal vegetative growth, decreased sporulation, absent invasive growth, altered autophagy and mitophagy, increased or decreased cell death, abnormal nuclear and mitochondrial morphology, delayed endocytosis, and reduced biofilm formation. It is also associated with decreased protein secretion, abnormal Golgi morphology, and altered viability. Related genes in other species link the family to apoplastic effector functions and the enzyme classification 3.4.16.6.